Benefits of Temporal Interference Brain Stimulation Techniques

Recently, a team led by Liu Yu and Wang Xiaohui from Shanghai University of Sport published an article in the journal Brain Stimulation titled Temporally interfering electric fields brain stimulation in primary motor cortex of mice promotes motor skill through enhancing neuroplasticity. 

This work first confirmed that continuous 7-day non-invasive TI stimulation (once a day, 10 minutes each time, ∆f=20Hz) in the M1 area can effectively enhance the mouse’s strength, balance, endurance, coordination, and other motor abilities. The mechanism of action is related to its enhancement of neuronal excitability and synaptic plasticity, as well as improvement in synaptic microstructure. Compared with traditional tACS, TI stimulation can better enhance the motor skills of mice. Experimental techniques used in the research include temporal interference stimulation, transcranial alternating current stimulation, multichannel fiber photometry system, metabolomics, Western blot, laser confocal, Liquid Chromatography-Mass Spectrometry, and animal behavioral evaluation. In this study, researchers used the fiber photometry system produced by RWD, which provided support for the smooth progress of the experiment.

RWD multichannel fiber photometry system in Professor Wang’s laboratory 

You can read more about this study on the site of our partner RWD Life Science Co., Ltd.