Sophisticated patch-clamp electrophysiology data acquisition and analysis software
Program for Patch-clamp Analysis with the Clampfit Advanced Analysis Module
The industry-leading patch-clamp electrophysiological data acquisition and analysis application, known as the pCLAMP™ Software Suite, is used to control and record voltage-clamp, current-clamp, and patch-clamp investigations. The software bundle comprises of the Clampex 11 data gathering program, the AxoScope 11 background recording software, the Clampfit 11 data analysis software, and the optional Clampfit Advanced Analysis Module.
Create Complex Protocols Quickly
With 50 epochs available instead of 10, the improved protocol editor gives programmers the freedom to create longer, more complex protocols.
Streamline Workflows*
The use of batch analysis macros makes it possible to analyze data files in groups without having to individually declare the parameters for each data set.
Analyze Faster*
Automatic event detection examines post-synaptic data as well as spontaneous and induced action potentials. Determine events using a variety of criteria.
Features
Tools for Extensive Analysis
Many analysis tools are included in the software, such as 24 cursor pairs for searching for locations of interest, graph displaying tools including the I-V plot and histogram, and more.
Enhanced Visualization
Several channels can be controlled more easily thanks to the membrane testwindow's simultaneous display of up to eight channels.
Enhanced Gap-free Mode
A straightforward continuous "chart-recorder" excellent for tracking single channel events, minis, and other unplanned activity. Program digital or analog outputs as well as epochs designed for protocol editors can be used.
Population Spike Analysis*
The amplitude, area under the curve, half-width, decay and rise duration, decay and rise slope, spike coastline, and paired pulses are all automatically calculated by this program.
Action Potential Analysis*
Automatic detection and analysis of amplitude, APD90, rise and decay duration, rise and decay slope, peak-to-peak frequency and time, among other parameters, are provided by this function.
Batch Analysis*
It is not necessary to define parameters for each data set when using macros for batch analysis. Several data sets can be analyzed automatically using saved macros.
*Clampfit Advanced Analysis Module only
Specifications & Options of pCLAMP 11 Software Suite
System Requirements
Operating system
- Minimum: Windows 7 Pro (32-bit)**
- Recommended: Windows 10 Pro (32- or 64-bit)**
CPU
- Minimum: PC with 2 GHz processor
- Recommended: PC with 2.0 GHz (or faster) Duo Processor
RAM
- Minimum: 1.2 GB RAM
- Recommended: 4 GB or higher
Display
- Minimum: 1440 x 900 display
- Recommended: 1920 x 1080 display or higher
Ports
- Minimum: 1 USB 1 port (for security key dongle), 1 USB 2.0 port (for Digidata digitizers)
- Recommended: 3 USB 2.0 ports
Compatible instruments
- Digidata 1550B 8-Channel Digitizer
- Digidata 1440A 16-Channel Digitizer
- MiniDigi 1B Two-Channel Digitizer
- Axoclamp 900A Microelectrode Amplifier
- Axopatch 200B Microelectrode Amplifier
- MultiClamp 700B Microelectrode Amplifier
- Most BNC-telegraphed amplifiers also supported*
*Supports all previous versions in a model line.
**We only support Professional, Enterprise, and Ultimate editions but not Home edition.
Axon™ pCLAMP®, Axon™ DigiData™ and Windows Operating System Compatibility Table
The compatibility of the pCLAMP software with several AXON digitizers and Windows operating systems may be found in the table below.
pCLAMP
|
MiniDigi
|
DigiData 1200
|
DigiData 132x
|
DigiData 1440
|
Digidata 1550 series
|
Windows OSa
|
8.xb
|
No
|
Yes
|
Yes
|
No
|
No
|
95, 98, ME, NT4.0, 2000, XP
|
9.xc
|
Yes
|
Yes
|
Yes
|
No
|
No
|
98, ME, 2000, XP
|
10.xd
|
Yesh
|
No
|
Yesg
|
Yesf
|
Yesf
|
2000, XP sp3, Vista, Windows 7 & Windows 10e (32 & 64-bit)
|
11.x
|
Yesh
|
No
|
No
|
Yes
|
Yes
|
Windows 7 & Windows 10e (32 & 64-bit)
|
Notes:
a.) Only computers running genuine versions of Windows are supported; emulators and virtual machines are not supported. Only U.S. versions of the Windows operating system are fully supported. Only installers with pCLAMP version 10.3 or higher can support 64-bit operating systems.
b.) Update from 8.0 or 8.1 to 8.2 is free. Only the 32-bit installer of 8.2 runs on Windows XP (see download link above).
c.) Update from 9.0 or 9.1 to 9.2 is free. pCLAMP 9 software is not supported for use under Windows 7 (32- or 64-bit versions).
d.) All updates within 10.x (e.g. from 10.0 to 10.7) are free.
e.) Windows Home Edition is not supported.
f.) Digidata 1440, 1550, 1550A, and 1550B are supported on 10.7.
g.) Use of the Digidata 1320A, 1321A or 1322A on 64-bit Operating Systems is not supported. The Digidata 132x series are only supported up to pCLAMP versions 10.3.
h.) MiniDigi 1B is required for use under 64-bit Operating Systems.