Vessel Calcium, Diameter and Flow System

A comprehensive data acquisition system for pressurized vessel flow characterization and diameter and fluorescence measurements

IonOptix has integrated pressured blood vessel fluorescence and diameter measurements into our Myocyte Calcium and Contractility System. IonOptix's new vessel-specific dimensioning software, VesAcq, records quantitative fluorescence, most frequently from calcium probes, while simultaneously tracking the blood vessel's outer and/or luminal diameters, wall thickness, and cross-sectional area from the digitized frame. Important artery flow parameters like shear stress and vascular resistance are measured in real-time by new FloAcq program.

In order to provide an integrated workstation capable of exact, synchronized data capture, IonOptix will collaborate with the maker of your myograph system. The manufacturer  is able to provide real-time recording of all vessel myograph outputs, including pressure, force, temperature, and pH, as well as calcium and diameter, using FSI interface box and a technology that permits the pressurization of microvessels. IonOptix  may connect the system to an already installed microscope or include a microscope with the system.

Your preparations are used when IonOptix installs it's comprehensive systems to enable you get going as soon as feasible. Additionally, they provide limitless phone and email support for the duration of your system should you require it.

FEATURES

• Calcium and diameter data are acquired simultaneously and in real time, and/or the flow parameters are characterized.
• Provides real-time pressure data gathering by integrating with your pressure myography equipment.
• Measures media-to-lumen ratio, inner/outer vessel diameter, left/right average wall thickness, inner/outer cross-sectional area.
• Reynolds number, vessel wall shear stress, mean pressure, flow velocity, and vascular resistance are used to describe flow.

COMPONENTS

Digital vessel cameras, microscopes, and fluorescence components make up the majority of vessel system components. IonOptix' systems can communicate with a wide range of extraneous parts, like pressure myography chambers.

Microscope

For integrated photometry and dimensioning measurements, the IonOptix-configured Motic AE31 inverted microscope offers the perfect working environment. In order to function as the imaging component within the systems, this microscope has been designed to incorporate several distinctive IonOptix optical components and interfaces.

Light Source

Your unique research requirements guide the selection of the fluorescence excitation light source, which can be set up for practically any dye or dye combination. Monochromatic LEDs, the extremely quick HyperSwitch, or the more reasonably priced MuStep are all possibilities.

Sensors

Fluorescence photometry is measured with a photomultiplier tube, and vessel geometry is measured using the VesCam. Together with your vessel chamber pressure readings, a flow meter can be included to assess flow characteristics.

Interfaces

By enabling communication between hardware and the computer, the FSI connects the various system parts and enables simultaneous control of vessel dimension, calcium, and/or flow measurements as well as inputs and outputs for external devices.

SOFTWARE

In order to meet all of your vessel measurement demands, IonOptix offers a comprehensive range of software acquisition modules. Track the dimensions of the vessels using VesAcq, and record quantitative fluorescence with PMTAcq and/or arterial flow characteristics with FloAcq at the same time. IonWizard trace recording can be used to synchronize all of these with external signals, such as inlet/outlet pressure from a myograph chamber.