• Our e-mail:
Patchliner

Patchliner – Smart and Adaptable Tool

With Nanion Patchliner you can have up to eight cells recorded at once. It's the most versatile automatic patch clamp system available.

The Most Versatile Automatic Patch Clamp System Available

A completely automated patch clamp system called the Patchliner can record from four or eight cells at once. This device is the most adaptable APC system available because to the HEKA EPC10 amplifiers, which offer complete control over pipette speed, real-time protocol switching capabilities, and adjustable add-ons for dynamic clamp and temperature control. Since its launch in 2006, the Patchliner has been tried and tested and is well-liked by CROs, industry, and academics.

Key Features:

  • Up to eight cells recorded at once
  • Increased success rates
  • Standard voltage and current clamp
  • Advanced temperature regulation
  • Dynamic clamp, if desired
  • Quick external application
  • Reduced duration of exposure
  • Compound application without limits

The Patchliner is a durable and versatile tool that may be used for a variety of tasks, including common assays like safety screening of cardiac ion channels in compliance with the CiPA program, as well as complicated assays like heat activation and basic research on ion channel biophysics and mechanisms of action.

Available in 4 or 8 channel versions, the Patchliner is an automated patch clamp system with a medium throughput. The Tecan robot is programmed to add solutions, cells, and compounds, and the PatchMaster software is used to acquire data, all through the use of the PatchControlHT software. The Patchliner's consumable, NPC-16 chips, can be placed on the chip cart and left to operate unsupervised for 48 recordings.

The Tecan pipetting robot, HEKA EPC10 amplifiers, NPC-16 chips, Reagent beginning kit, and all necessary software are included in the full system that is delivered with the Patchliner. To increase the number of possible experiments, add-ons for dynamic clamp (Dynamite8), temperature control, and cooled CellHotel are also offered.

Nanion's devoted staff of engineers and electrophysiologists is committed to ongoing internal assay research, software, and hardware innovations, guaranteeing prompt and specially designed solutions for your test requirements.

Would you like high-quality data from a dependable automatic patch clamp system?

A completely automated planar patch clamp device, the Patchliner can record from up to eight cells at once. One of the most adaptable patch clamp devices available is the Patchliner, with its enormous experimental freedom and gigaseal data quality.

 

Specifications of Nanion Patchliner

Average whole-cell stability: >30 minutes

Successful whole-cell recordings: 70–90%

Throughput: 250–600 data points per day

Seal resistance: >1 GΩ

Series resistance: <10 MΩ

Chip resistance: low, medium, high, ultra-high, multi-hole (4X)

Perfusion time constant: <20 ms

Minimum exposure time: 200 ms

Amplifier channels: 4 or 8

Temperature control: up to 60 °C (heating only)

Current clamp: integrated as standard

CoolingPlate: cooling of cell storage and compounds (optional)

 

The Patchliner includes:

  • Patchliner Quattro: 4 amplifier channels
  • Patchliner Octo: 8 amplifier channels
  • 1–2 HEKA EPC10 Quadro amplifiers
  • Windows 10 OS with PatchControlHT and PatchMaster software
  • Patchliner Data Analysis Package (incl. Igor Pro)
  • NPC-16 borosilicate recording chips
  • Reagent starter kit
  • On-site installation support
  • 1 year warranty with further optional comprehensive service plans available

You can also visit site of the manufacturer.


Warning: Undefined variable $endscript in /data01/virt29233/domeenid/www.tregoland.eu/htdocs/templates/footer.php on line 44