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Model 1600

Neuroprobe Amplifier Model 1600

The Model 1600 microelectrode amplifier is designed for intracellular potential recording. It is designed in a single unit with a display panel for displaying the membrane potential, injected current, and electrode resistance.

The Neuroprobe Amplifier Model 1600 was created to exceed the strict specifications of intracellular neurological studies and offer the research scientist diversity, precision, and simplicity of use.

The device combines a high input impedance amplifier with bridge balance, current injection, and circuitry that allows simultaneous recording and stimulation through the same electrode. Without the need for an additional bridge or a differential input oscilloscope, the internal Dual-Function Transient Control and the DC balance Control ensure highly precise records during current injection. The DC Offset, DC Balance, Current Injection, and Capacitance Compensation controls are all high-resolution ten-turn potentiometers. Using the internal 100 Hz test pulse, you can determine the electrode resistance and modify the capacitance compensation. A simple to use Digital Panel Meter generates a highly precise display of electrode resistance, injected current, or membrane potential.

The sophisticated current injection technology of the Neuroprobe Amplifier allows for external switching of both internal and external current sources with 0.1 nA precise adjustment. Prior to injection, the Digital Panel Meter can show the total current from all sources. The users can inject the precise amount of current they want thanks to this functionality. Additionally, the user has the option of choosing between brief or continuous injection, depending on the needs of the experiment.

For iontophoretic injection of medications or dyes or for any other application requiring currents greater than those offered by the Neuroprobe Amplifier, this Iontophoresis Adapter enables the researcher to apply higher voltages to the micropipette.

Model 1600 Headstage

A Model 1600-compatible headstage (Catalog#: 681500) must be purchased for appropriate operation.

Current Input

  • Impedance: 1011?„¦
  • Capacitance: Adjustable to zero
  • Working Range: ± 2.5 V
  • Maximum Range: ± 10 V
  • Iontophoresis Adapter Input: ± 200 V

Current Injection: External Source

  • Input Impedance: 20 k?„¦
  • Frequency Range: DC to 250 kHz
  • Low Range Maximum Current: 10 nA/V
  • Low Range Maximum Voltage: lesser of ± 10V and (± 2.5 x 108 V?„¦)/(electrode resistance)
  • High Range Maximum Current: 100 nA/V
  • High Range Maximum Voltage: lesser of ± 10V and (± 2.5 x 107 V?„¦)/(electrode resistance)

Current Injection: External Source

  • Low Range Maximum Current: lesser of ± 100 nA and 2.5 V/(electrode resistance)
  • Low Range Maximum Voltage: lesser of ± 1000 nA and 2.5 V/(electrode resistance)

Current Gate

  • ON Signal: + 2.5 V (Step with rise time 10 µsec)
  • OFF Signal: +0.6 V
  • Maximum Input: ± 15 V
  • Input Impedance 20 k?„¦

Electrode Test: External Signal Source

  • Input Impedance: 10 k?„¦
  • Input Voltage Range: ± 10 V
  • Low Range Scale Factor (x1 Output): 1 mV/M?„¦/(input voltage)
  • High Range Scale Factor (x1 Output): 10 mV/M?„¦/(input voltage)

Electrode Test: Internal Signal Source

  • Signal: 100 Hz Square Wave
  • Low Range Scale Factor (x1 Output): 1 nA p-p produces 1 mV/M?„¦
  • High Range Scale Factor (x1 Output): 10 nA p-p produces 1 mV/M?„¦

Signal Processing: Input Bias Current

  • Optimal: Adjustable to Zero
  • Maximum without adjustment, Low Range: 3x10-12 Amp
  • Maximum without adjustment, High Range: 3x10-11Amp
  • Drift vs Temperature, Low Range: 1x10-13 Amp/°C
  • Drift vs Temperature, High Range: 1x10-12 Amp/°C
  • Drift vs Time, Low Range: 3x10-13 Amp/12 hours
  • Drift vs Time, High Range: 3x10-12 Amp/12 hours

Signal Processing: Frequency Response

  • Frequency Range: DC to 325 kHz

Signal Processing: Rise Time

  • Square Wave (500 mV) 50 ?„¦ Source: 0.8 µsec (10% to 90%)
  • Square Wave (500 mV) 20 M?„¦ Source: 7.0µsec (10% to 90%)

Signal Processing: Zero Stability

  • Stability vs Temperature: 200 µV/°C
  • Stability vs Time:1 mV/12 hours

Signal Processing: Low Pass Filter

  • Cut-off Frequencies (-3 dB): 1, 2, 5, 10, 20, 50, 100 kHz
  • Slope: -12 dB/octave

Signal Processing: Notch Filter

  • Center Frequency: 50 Hz or 60 Hz (factory preset)
  • Q: 10
  • Rejection: -50 dB

Signal Processing: Capacitance Compensation

  • Range: -4 pF to +30 pF

Signal Processing: Internal Calibration Voltage

  • 10mV: ± 1%
  • 1000mV: ± 1%

Signal Processing: Noise

  • 0 ?„¦ Source: 13 µV RMS (10Hz to 50kHz)
  • 1 M?„¦ Source: 79 µV RMS (10Hz to 50kHz)
  • 20 M?„¦ Source: 310 µV RMS (10Hz to 50kHz)

Signal Processing: DC Balance

  • Low Range: up to 500 M?„¦
  • High Range: up to 50 M?„¦

Output x1

  • Voltage Gain: 1.00 ± 0.1%
  • Maximum Voltage: ± 10V
  • Impedance: 220 ?„¦
  • DC Offset Range: 0.0 V to ± 1.0 V

Output x10

  • Voltage Gain: 10.00 ± 1.0%
  • Maximum Voltage: ± 10 V
  • Impedance: 220 ?„¦
  • DC Offset Range: 0.0 V to ± 10.0 V

Output: Current Monitor

  • Low Range Scale Factor: 10 mV/nA
  • High Range Scale Facto: 1 mV/nA
  • Maximum Output: ± 1.0 V
  • Output Impedance: 1 k?„¦

You can also visit site of the manufacturer.

A-M Systems, LLC
We are a distributor of A-M Systems, LLC in Ukraine, Kazahstan and Europe

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