High-Precision Vibrating Microtome, Model 9000SMZ

Key features

• With over 40 years of experience and more than 4000 publications on vibrating microtomes.
• 5-Year Warranty.
• Demonstrated high-quality slices that maintain high cell viability.
• No chatter marks present.
• Adjustable blade frequency and amplitude to accommodate all types of tissue.
• Accurate control of advance speed, which can be modified during slicing, ensuring the perfect slice.
• Measurement and correction of blade Z-axis deflection (as precise as 0.1µm), crucial for producing quality slices.
• Slice window mode enables rapid, automatic sectioning.
• Enhanced visibility of tissue; positional adjustments can be performed during the slicing process.
• Ability to store up to 8 user-defined slice profiles for convenient recall.
• Slice Quality Control Validation Data.

The New Standard in Precision Tissue Slicing

Cutting-edge Vibratome Technology for Life Science and Biomedical Research

The Campden 9000SMZ Vibratome represents the most sophisticated vibrating microtome, designed for the accurate sectioning of both live and fixed brain tissue. It is relied upon by laboratories engaged in neuroscience, cardiac, lung, liver, organoid, and plant research globally.

When the integrity of your tissue slices is critical to your research, settling for less is not an option. The 9000SMZ Vibrating Microtome from Campden Instruments provides unparalleled control, exceptional slice quality, and tissue viability — making it the premier vibratome for use in electrophysiology, imaging, pathology, toxicology, and organ research.

What is a Vibratome?

A vibratome is a specialized type of microtome that sections biological tissue using a vibrating blade made of stainless steel or ceramic. Unlike rotary microtomes, cryostats, or methods involving paraffin embedding, a vibratome facilitates the preparation of unfixed or lightly fixed tissue sections without requiring freezing or wax embedding.

Why the 9000SMZ is the Premier Vibratome for Researchers

Whether you are preparing slices of brain, kidney, lung, liver, retina, cardiac, pancreatic, brain organoids, tumor, or plant tissue, the 9000SMZ delivers the precision and reproducibility required by modern life sciences. 

Explore New Features

Exceptional Tissue Integrity Across Various Applications

• Ultra-low blade Z-axis deflection reduces mechanical damage.
• Preserves structural and cellular viability across a broad spectrum of soft tissues.
• Perfect for acute slicing, live tissue studies, ex vivo analysis, and long-term cultures.

Intelligent, Automated Control System

• Touchscreen interface featuring programmable slicing profiles.
• Real-time feedback on blade amplitude, frequency, and advance rate.
• Reduces training time and variability between users.

High-Precision Engineering

• Advance speed resolution of 10µm/s ensures reproducible section thickness.
• Vibrating blade holder exhibits less than 0.1µm (100nm) deviation from the intended path.
• Compatible with various tissue sizes and embedding media.

Integrated Tissue Protection

• Built-in cooling tray sustains physiological conditions.
• Optional integrated Peltier cooling device.
• Optimized for prolonged slicing sessions without sacrificing slice quality.

Engineered for Scientists, Supported by Innovation

Campden Instruments has partnered with leading researchers across various fields to develop a vibratome that addresses real-world laboratory challenges. With the 9000SMZ, you can anticipate:

• Cleaner slices
• Enhanced reproducibility
• Confidence from the very first cut.

One Vibratome, Limitless Applications

• Neuroscience & electrophysiology
• Renal, Precision Cut Liver Slices, Precision Cut Lung Slices, and cardiovascular research (living myocardial slices).
• Plant root and leaf sectioning.
• Retinal and ocular tissue preparation.