BA-01M – Bridge Amplifier Module

Npi's BA-01M bridge amplifier module serves as a high-impedance intracellular amplifier with a wide bandwidth, designed for recordings utilizing sharp microelectrodes or suction (patch) pipettes.

Overview
Specifications
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Advantages of the BA-01M

Accurate current clamp functionality
User-friendly cell penetration mode featuring sharp microelectrodes
Compatible with any data acquisition system
Also offered as a 19" stand-alone device

Intracellular Bridge Mode Amplifier

The BA-01M bridge amplifier module serves as a high-impedance intracellular amplifier with a wide bandwidth, designed for recordings utilizing sharp microelectrodes or suction (patch) pipettes. Presently, BA amplifiers are employed in both vertebrate (such as rat, mouse, cat, fish, etc.) and invertebrate (including leech, crab, snail, insect, etc.) neurons, muscle cells, other excitable tissues, and plant cells.

The BA-01M EPMS module shares the same specifications as the BA-01X 19" stand-alone device, with the exception of having a single current input range (1 nA/V), one potential output (x10 mV), one bridge balance range (0-1000 MΩ), and lacking oscillation shut-off.

Features:

Authentic current clamp operation with recorded membrane potential and complete elimination of series resistance
Compatible with sharp microelectrodes and patch pipettes in both whole-cell and perforated-patch configurations
Digital displays for current, voltage, and electrode resistance
Oscillation shut-off unit to prevent cellular damage
Buzz and electrode clear functionality
Digital adjustment of gated stimulus amplitude, along with settings and digital readout of holding current
Now featuring an enhanced (x10) current range for electroporation and iontophoresis

Specifications of the BA-01M

Input voltage range: ±1 V

Operating voltage: ±15 V

Enclosure: Size: 23 x 70 x 26 mm, grounded

Dovetail: Size: 70 mm x 17 mm x 3 mm

Electrode connector: BNC with driven shield

REF connector: SMB connector

Ground connector: 2.4 mm connector

Input resistance (CC): >1013 Ω (internally adjustable)

Current range:

±10 nA max. (100 MΩ feedback, X1 CURRENT RANGE)
±100 nA max. (100 MΩ feedback, X10 CURRENT RANGE)

OFFSET: range ±200 mV, ten-turn control

CAPACITY COMPENSATION: range 0 – 30 pF, ten-turn control

BIAS: range ±200 pA, ten-turn control

BRIDGE BALANCE:

0-100 MΩ (range switch set to 10 MΩ)
0-1000 MΩ (range switch set to 100 MΩ)
adjustable with ten-turn control

Electrode clear circuit: Application of max. DC currents (-Imax or +Imax)

Cell penetration: BUZZ, duration ~2.5 – ~100 ms

Sensitivity 1 mV / MΩ application of square current pulses ±1 nA

Display: 3 ½ digit, XXX MΩ, activated by key switch (same as POTENTIAL display)

Full power bandwidth (REL = 10 kΩ): >10 kHz

rise time (10% – 90%), square pulse, 1 V pp:

40 µs (voltage), 30 µs (current) (REL = 100 MΩ)

25 µs (voltage and current) (REL = 5 MΩ)

Output impedance: 50 Ω

Max. voltage: ±12 V

Current output: BNC connector, sensitivity 0.1 V/nA,

Current display:

3 ½ digits, XX.XX nA, resolution 10 pA (X1 CURRENT RANGE)
3 ½ digits, XXX.X nA, resolution 100 pA (X10 CURRENT RANGE)

POTENTIAL OUTPUT: BNC connector, sensitivity 10 V/V

Potential output resolution in AC: 50 µV

Display mV/MΩ: 3 ½ digits, XXXX mV or XXX MΩ

Display current:

3 ½ digits, XX.XX nA (X1 CURRENT RANGE)
3 ½ digits, XXX.X nA (X10 CURRENT RANGE)

Input impedance analog: 100 kΩ

Input range: ±12 V

Input impedance digital (TTL): 10 kΩ

Input range TTL: 0-5 V

Current stimulus input CC:

via BNC connectors
X1 CURRENT RANGE: 1 nA/V
X10 CURRENT RANGE: 10 nA/V

Holding current:

X1 CURRENT RANGE: ±10 nA
X10 CURRENT RANGE: ±100 nA
Adjustable with ten-turn control

Step gate input: via BNC connector (TTL)

Gated stimulus CC:

X1 CURRENT RANGE: resolution: 10 pA, range: ±10 nA
X10 CURRENT RANGE: resolution: 100 pA, range: ±100 nA
with digital control of current step size

Polarity: selectable with toggle switch

Dimensions: Module for EPMS-07 system, width: 2 U

Power requirements: Supply power is provided by EPMS-07

You can also visit site of the manufacturer.

BA-01M – Bridge Amplifier Module

Advantages of the BA-01M

Intracellular Bridge Mode Amplifier

Features:

Specifications of the BA-01M

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