Vibrotome Campden 7000smz-2

The world's best tissue slicer for preparing tissues for visual patch clamping or high resolution imaging is Campden's top of the line high precision vibrating microtome, also known as a vibrotome. About 450 labs have chosen the 7000smz series Vibrating Microtome as their instrument of choice for the past 10 years!

Campden's microtomes have been used in studies describing sectioning for visual patching of neurological tissue, heart, lung, and tissue scaffolds. With greater precision and lower cost, the 7000smz-2 microtome represents considerable advancements.

The 7000smz-2 microtome's vibrating mechanism produces exceptional accuracy while operating almost silently. Each machine is provided with a z-axis calibration checker and is validated by manufacturer's in-house measurement instruments prior to shipping.

Since the publication of Geiger et al. (2003), there has been much discussion regarding the impact of excessive Z-axis deflection on the health and viability of the tissue preparation. The Campden 7000smz-2 tissue slicer, with 1 µm Z-axis deflection across a wide range of vibration speeds and amplitudes, consistently produces healthy, viable sections.

The user interface is simple and flexible (unlike earlier models, it lacks a foot switch) and provides simple operation at the touch of a button or a variety of programmable options for the experienced user. In addition to offering ≤ 1µm performance right out of the box, the Campden 7000smz-2 also offers lifetime of performance because the advanced vibrating mechanism lacks bearings and other wear-prone components. As a result, it will continue to perform at its previous level for many years, offering you stability in your biological preparation without the need for pricy maintenance.

The tissue must be held at or near 4° C during the cutting process. This can be accomplished either passively, using a known quantity of ice to maintain the cooled area, or electronically, using a thermoelectric Tissue Bath Cooler (7610A).

To ensure that the machine's grinding and honing facets for the blade edge are matched to the blade's downward angle of orientation to the tissue, Campden designed microtome blades made of ceramic and stainless steel. When cutting brain tissue that is older than 30 days, the ceramic blades offer a distinct advantage. These ceramic microtome blades also have the benefit of not needing to be replaced after each tissue sample, in contrast to stainless steel blades.

An LED cold light, a magnifier, or a scope for clear observation during slicing are further alternatives. shown with a temperature controller and an optional Slice incubator.

Featured Component: Tissue Slice Recovery Chamber

The Model 7470 Temperature-controlled Slice Holding Chamber, which is displayed next to the tissue slicer in the image above, was created as an add-on for the Campden Instruments line of tissue slicers. With an aeration supply to enable for recovery from slicing as well as incubation during the experimental day, they are made to keep and preserve tissue slices in six sub-chambers at physiological temperatures.

Features

• Is equipped with a z-axis calibration unit
• Z-axis blade minimizer adjustment
• Angle of the blade holder to the user's needs
• Set the start and stop positions for the blade's movement.
• 50 to 120 Hz of vibration frequency
• Amplitudes of 0.5 to 2.5 millimeters
• Controllable blade advance at 10 µm/s
• Either a manual or automatic process
• "Auto" programming through the first slice's storage
• Easily removable ice bath for cleaning
• Scope with optional LED light for unobstructed observation